What in the World is Wharton's Jelly

Wharton's jelly is a gelatinous substance within the umbilical cord and it contains a rich concentration of stem cells, growth factors, and signaling molecules. We will come back to this!!...
...I have a strong appreciation for skin rejuvenation treatments. Now in my 40s, I’m aware that my collagen production began to decline in my 20s, and I’m noticing the effects of aging and sun damage on my skin.
When I first heard about exosomes, I was immediately intrigued. The idea that they can enhance the results of microneedling for even better results? Yes please!
Microneedling, also known as collagen induction therapy, is a minimally invasive treatment that uses tiny, sterile needles to create micro-injuries in the skin’s surface. These controlled micro-injuries stimulate the skin's natural healing process, encouraging the production of collagen and elastin. This helps improve skin texture, reduce fine lines, and promote a more youthful, rejuvenated appearance. The treatment is effective for a variety of skin concerns, including acne scars, pigmentation, and overall skin laxity.
How can we enhance microneedling with exosomes?
This brings us back to Wharton's Jelly.
The exosomes used in DP Dermaceuticals’ EXO-SKIN are sourced from Wharton’s jelly. Rich in growth factors, stem cells, and signaling molecules, Wharton’s jelly is a powerful natural resource for skin regeneration. The exosomes extracted from this tissue are tiny vesicles that carry essential biological information, promoting cellular communication and accelerating the skin’s natural repair processes. When applied during microneedling, these exosomes help enhance collagen production, improve skin texture, and stimulate overall rejuvenation, making the treatment even more effective and delivering faster, more visible results.
I find analogies really helpful for understanding complex ideas. In a recent webinar I watched, they used a great one to explain the concept. Imagine you want to renovate your kitchen. You’ve got some tools in the garage, maybe some leftover paint and materials—enough to make a decent go of it. But now, imagine exosomes as an Ikea flat-pack. It comes with everything you need in one box: the tools, the materials, and clear step-by-step instructions. It’s a more efficient, streamlined way to get the job done. In a biological context, exosomes provide a well-organised, efficient delivery system that ensures the right components reach the right place at the right time.
Doesn't the idea of using stem cells derived from Wharton's jelly sound strange, though?
I hear you… Even though the exosomes are derived from Wharton's Jelly, they are then carefully reverse-engineered to remove all human cells, DNA, or identifying material. The result is a safe, cell-free formula that contains only the beneficial signals—like proteins and growth factors—that support skin repair and rejuvenation. This approach makes the formulations non-immunogenic, biocompatible, and safe for all skin types, aligning with both ethical and scientific standards.
I gave it a go, and here's what happened...
I noticed the recovery time was much faster because the ampoule of exosomes also contains ingredients for faster wound healing. Initially, my skin felt dry and tight for about two days, but soon after, I started noticing its smooth texture. I’m planning to continue taking progress photos to track the results. At home, I’m using the recommended EXO-SKIN serum morning and night to maintain the benefits.
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